EVERYTHING YOU NEED TO KNOW ABOUT CBDA - EDUCATIONAL PURPOSES
- Marison Miller
- Feb 17, 2022
- 2 min read
Updated: Feb 21, 2022

Everyone has heard of CBD. You've likely seen CBD products on shelves in stores near you. CBD is everywhere.
CBDA is not interchangeable with CBD. They're different compounds, although they do have a close relationship.
The main difference is that CBDA is a precursor to CBD. You create CBD by heating CBDA or raw CBD.
CBD and CBDA are thought to cause their signature effects by activating our 5-HT1A serotonin receptors. You've likely heard of serotonin, as it is a vital neurotransmitter in our brains that is closely involved in regulating our mood, sleep, anxiety, and even nausea.
CBD is noted to help with things like anxiety, depression, inflammation, and even a rare form of childhood epilepsy.
CBDA RESEARCH:
One study found that CBDA produces antidepressant effects on rats at doses 10 to 100 times lower than CBD.
This is due to CBDA's relationship with serotonin receptors. For this same reason, CBDA is further researched as an anti-nausea drug, with one study finding CBDA more effective at reducing nausea than CBD.
One study showed that CBDA could act as an effective anti-inflammatory agent. In this study, CBDA was found to be more proficient than THC at blocking COX-2, an enzyme produced when inflammation is present. The same study found that the acidic component of CBDA plays a vital role in its ability to inhibit COX-2.
Another study found that CBDA was a thousand times more powerful than CBD for anti-nausea and anti-anxiety effects. In this study on animal models, CBDA displayed "significantly greater potency at inhibiting vomiting in shrews and nausea in rats" when compared to CBD.
Additionally, CBDA appears to share most of the benefits CBD users seek, such as anti-anxiety properties and more.
NEWS 1/12/2022: An article was written on Forbes.com "Study Finds Cannabis Compounds Prevent Infection By Covid-19 Virus shares some new, interesting findings of CBDA and mentions - "…researchers found that two cannabinoid acids commonly found in hemp varietals of cannabis, cannabigerolic acid, or CBGA, and cannabidiolic acid, also known as researchers found that two cannabinoid acids commonly found in hemp varietals of cannabis, cannabigerolic acid, or CBGA, and cannabidiolic acid, also known as CBDA, can bind to the spike protein of SARS-CoV-2, the virus that causes Covid-19. By binding to the spike protein, the compounds can prevent the virus from entering cells and causing infection, potentially offering new avenues to prevent and treat the disease." The article goes on to say - "Orally bioavailable and with a long history of safe human use, these cannabinoids, isolated or in hemp extracts, have the potential to prevent as well as treat infection by SARS-CoV-2," the researchers wrote in an abstract of the study."
SUMMARY
As you can see, CBDA does indeed have its own unique potential in the growing cannabinoid industry.
For those of you who are just dipping your toes into the CBD/health supplement waters, CBDA may indeed offer another good option to add to your health and wellness routine. CBDA might be what you need to optimize your wellness routine! Especially when CBD & CBDA come in the same bottle.
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